Drug General Information
Drug ID	D04WIA
Former ID	DNC011956
Drug Name	2-Pyridin-2-yl-6H-pyrazolo[1,5-c]quinazolin-5-one
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[534157]
Structure		Download 2D MOL 3D MOL
Formula	C15H10N4O
Canonical SMILES	C1=CC=NC(=C1)C2=CC3=C4C=CC=CC4=NC(=O)N3N2
InChI	1S/C15H10N4O/c20-15-17-11-6-2-1-5-10(11)14-9-13(18-19(14)15)12-7-3-4-8-16-12/h1-9,18H
InChIKey	LPUOGVWEOKCYCJ-UHFFFAOYSA-N
PubChem Compound ID	10587546
Target and Pathway
Target(s)	Gamma-aminobutyric acid receptor	Target Info	Inhibitor	[534157]
	Gamma-aminobutyric acid receptor subunit alpha-1	Target Info	Inhibitor	[534157]
KEGG Pathway	Neuroactive ligand-receptor interaction
	Retrograde endocannabinoid signaling
	GABAergic synapse
	Morphine addiction
	Nicotine addiction
Reactome	Ligand-gated ion channel transport
	GABA A receptor activation
WikiPathways	SIDS Susceptibility Pathways
	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
	Iron uptake and transport
References
Ref 534157	J Med Chem. 1996 Jul 19;39(15):2915-21.Synthesis and binding activity of some pyrazolo[1,5-c]quinazolines as tools to verify an optional binding site of a benzodiazepine receptor ligand.
Ref 534157	J Med Chem. 1996 Jul 19;39(15):2915-21.Synthesis and binding activity of some pyrazolo[1,5-c]quinazolines as tools to verify an optional binding site of a benzodiazepine receptor ligand.

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