Drug General Information
Drug ID
D05ARI
Former ID
DNC011847
Drug Name
Propyl-(4,5,6,7-tetrahydro-2H-indazol-5-yl)-amine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [533152]
Structure
Download
2D MOL

3D MOL

Formula
C10H17N3
Canonical SMILES
CCCNC1CCC2=C(C1)C=NN2
InChI
1S/C10H17N3/c1-2-5-11-9-3-4-10-8(6-9)7-12-13-10/h7,9,11H,2-6H2,1H3,(H,12,13)
InChIKey
PYXYUOJSCYNCKM-UHFFFAOYSA-N
PubChem Compound ID
Target and Pathway
Target(s) D(2) dopamine receptor Target Info Inhibitor [533152]
KEGG Pathway Rap1 signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Gap junction
Dopaminergic synapse
Parkinson's disease
Cocaine addiction
Alcoholism
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Dopamine receptor mediated signaling pathway
Nicotine pharmacodynamics pathway
Reactome Dopamine receptors
G alpha (i) signalling events
WikiPathways Hypothetical Network for Drug Addiction
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
Genes and (Common) Pathways Underlying Drug Addiction
GPCR ligand binding
GPCR downstream signaling
Nicotine Activity on Dopaminergic Neurons
References
Ref 533152J Med Chem. 1989 Oct;32(10):2388-96.Substituted 5-amino-4,5,6,7-tetrahydroindazoles as partial ergoline structures with dopaminergic activity.
Ref 533152J Med Chem. 1989 Oct;32(10):2388-96.Substituted 5-amino-4,5,6,7-tetrahydroindazoles as partial ergoline structures with dopaminergic activity.

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