Drug Information

Drug General Information
Drug ID
D05BWH
Former ID
DNCL001980
Drug Name
PRX-3140
Indication Alzheimer disease; Post-traumatic stress disorder [ICD9: 331, 309.81; ICD10:G30, F43.1] Phase 2 [548095]
Company
Nanotherapeutics
Target and Pathway
Target(s) 5-hydroxytryptamine 4 receptor Target Info Modulator [551175]
KEGG Pathway Calcium signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
5HT4 type receptor mediated signaling pathway
PathWhiz Pathway Excitatory Neural Signalling Through 5-HTR 4 and Serotonin
Reactome Serotonin receptors
G alpha (s) signalling events
WikiPathways Serotonin Receptor 4/6/7 and NR3C Signaling
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 548095Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800021864)
Ref 551175Clinical pipeline report, company report or official report of Nanotherapeutics.

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