Drug General Information
Drug ID
D05BXO
Former ID
DCL000321
Drug Name
Brasofensine
Synonyms
Brasofensine [INN]
Drug Type
Small molecular drug
Indication Parkinson's disease [ICD9: 332; ICD10:G20] Phase 2 [526004]
Company
Lundbeck
Structure
Download
2D MOL

3D MOL

Formula
C16H20Cl2N2O
Canonical SMILES
CN1C2CCC1C(C(C2)C3=CC(=C(C=C3)Cl)Cl)C=NOC
InChI
1S/C16H20Cl2N2O/c1-20-11-4-6-16(20)13(9-19-21-2)12(8-11)10-3-5-14(17)15(18)7-10/h3,5,7,9,11-13,16H,4,6,8H2,1-2H3/b19-9+/t11?,12-,13-,16?/m1/s1
InChIKey
NRLIFEGHTNUYFL-MTKJPOGLSA-N
CAS Number
CAS 171655-91-7
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Sodium-dependent serotonin transporter Target Info Modulator [526004]
KEGG Pathway Serotonergic synapse
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway 5HT1 type receptor mediated signaling pathway
5HT2 type receptor mediated signaling pathway
5HT3 type receptor mediated signaling pathway
5HT4 type receptor mediated signaling pathway
WikiPathways Monoamine Transport
SIDS Susceptibility Pathways
NRF2 pathway
Synaptic Vesicle Pathway
Serotonin Transporter Activity
References
Ref 526004Brasofensine NeuroSearch. Curr Opin Investig Drugs. 2000 Dec;1(4):504-7.
Ref 526004Brasofensine NeuroSearch. Curr Opin Investig Drugs. 2000 Dec;1(4):504-7.

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