Drug Information

Drug General Information
Drug ID
D05LBU
Former ID
DAP000723
Drug Name
Ticlopidine
Synonyms
Ticlid; Ticlopidina; Ticlopidinum; PCR 5332; Ticlid (TN); Ticlopidin-Puren; Ticlopidina [INN-Spanish]; Ticlopidine (INN); Ticlopidine [INN:BAN]; Ticlopidinum [INN-Latin]; Ticlopidin-Puren (TN); 5-((2-Chlorophenyl)methyl)-4,5,6,7-tetrahydrothieno(3,2-c)pyridine; 5-(2-Chlorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine; 5-[(2-chlorophenyl)methyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridine; 5-[(2-chlorophenyl)methyl]-6,7-dihydro-4H-thieno[3,2-c]pyridine
Drug Type
Small molecular drug
Indication Stroke [ICD9: 434.91, 437.6, 453, 671.5, 671.9; ICD10:I61-I63, I80-I82] Approved [536186], [542329]
Therapeutic Class
Fibrinolytic Agents
Structure
Download
2D MOL

3D MOL
Formula
C14H14ClNS
InChI
InChI=1S/C14H14ClNS/c15-13-4-2-1-3-11(13)9-16-7-5-14-12(10-16)6-8-17-14/h1-4,6,8H,5,7,9-10H2
InChIKey
PHWBOXQYWZNQIN-UHFFFAOYSA-N
CAS Number
CAS 55142-85-3
PubChem Compound ID
5472
PubChem Substance ID
9349, 5650061, 7980793, 8153361, 10526772, 11112786, 11466075, 11467195, 11485830, 15197138, 26751617, 29224517, 46504438, 47291227, 47440368, 47589090, 48110545, 48416628, 49698319, 50053360, 50085878, 50100522, 50139240, 50661300, 57288855, 57322795, 61110231, 85209800, 85787491, 90945105, 92308854, 92714062, 93167187, 93625532, 96025278, 99309316, 103219164, 104171328, 104309332, 117785149, 124882622, 124882623, 124882624, 124882625, 124882626, 124882627, 125203923, 126629679, 126666024, 128918298
ChEBI ID
ChEBI:9588
SuperDrug ATC ID
B01AC05
SuperDrug CAS ID
cas=055142853
Target and Pathway
Target(s) Platelet-activating factor receptor Target Info Modulator [556264]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Staphylococcus aureus infection
NetPath Pathway IL5 Signaling Pathway
Leptin Signaling Pathway
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (q) signalling events
Interferon gamma signaling
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Small Ligand GPCRs
Interferon gamma signaling
GPCR ligand binding
GPCR downstream signaling
References
Ref 536186Emerging drugs in peripheral arterial disease. Expert Opin Emerg Drugs. 2006 Mar;11(1):75-90.
Ref 542329(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7307).
Ref 556264Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.