Drug Information

Drug General Information
Drug ID
D05MCS
Former ID
DCL000413
Drug Name
GSK2190915
Drug Type
Small molecular drug
Indication Asthma [ICD10:J45] Discontinued in Phase 2 [548641]
Company
GSK
Structure
Download
2D MOL

3D MOL
Formula
C19H30ClN5O2
Canonical SMILES
CC1(CC(=O)N(C(=O)C1)CCCCN2CCN(CC2)C3=NC=CC=N3)C.Cl
InChI
1S/C19H29N5O2.ClH/c1-19(2)14-16(25)24(17(26)15-19)9-4-3-8-22-10-12-23(13-11-22)18-20-6-5-7-21-18;/h5-7H,3-4,8-15H2,1-2H3;1H
InChIKey
DGOCVISYYYQFEP-UHFFFAOYSA-N
PubChem Compound ID
55190
PubChem Substance ID
8184004, 12012960, 14854473, 34719098, 47206241, 57313720, 76292295, 104236673, 104306912, 117451361, 134339043, 134339044, 134339289, 134340051, 135013708, 160846455, 175266765, 179293617, 226656894, 252450948
SuperDrug ATC ID
N06AX19
SuperDrug CAS ID
cas=083928761
Target and Pathway
Target(s) Arachidonate 5-lipoxygenaseactivating protein Target Info Inhibitor [550963]
NetPath Pathway IL4 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
Leptin Signaling Pathway
PANTHER Pathway Inflammation mediated by chemokine and cytokine signaling pathway
WikiPathways Nuclear Receptors Meta-Pathway
Arachidonic acid metabolism
Eicosanoid Synthesis
Selenium Micronutrient Network
References
Ref 548641Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800027280)
Ref 550963Clinical pipeline report, company report or official report of GlaxoSmithKline (2009).

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