Drug General Information
Drug ID	D05NRI
Former ID	DIB001274
Drug Name	Ceronapril
Synonyms	Ceranapril; SQ-29852
Drug Type	Small molecular drug
Indication	Major depressive disorder [ICD9: 296.2, 296.3, 710.0; ICD10:F32, F33, M32]		Discontinued in Phase 2	[544627]
Company	Bristol-Myers Squibb Co
Structure		Download 2D MOL 3D MOL
Formula	C21H33N2O6P
Canonical SMILES	N1(C(=O)[C@@H](OP(=O)(O)CCCCc2ccccc2)CCCCN)[C@H](C(=O)O<br />)CCC1
CAS Number	CAS 111223-26-8
PubChem Compound ID	189729
Target and Pathway
Target(s)	Angiotensin-converting enzyme	Target Info	Inhibitor	[526817]
KEGG Pathway	Renin-angiotensin system
	Chagas disease (American trypanosomiasis)
	Hypertrophic cardiomyopathy (HCM)
PathWhiz Pathway	Angiotensin Metabolism
Reactome	Metabolism of Angiotensinogen to Angiotensins
WikiPathways	ACE Inhibitor Pathway
	Metabolism of Angiotensinogen to Angiotensins
References
Ref 544627	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000355)
Ref 526817	Radioimmunoassay for ceronapril, a new angiotensin-converting enzyme inhibitor, and its application to a pharmacokinetic study in healthy male volunteers. Ther Drug Monit. 1992 Jun;14(3):209-19.

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