Drug General Information
Drug ID
D05PHI
Former ID
DNC011727
Drug Name
2-(4-Methoxy-phenyl)-5-phenyl-thiazol-4-ol
Drug Type
Small molecular drug
Indication Discovery agent Investigative [531065]
Structure
Download
2D MOL

3D MOL

Formula
C16H13NO2S
Canonical SMILES
COC1=CC=C(C=C1)C2=NC(=C(S2)C3=CC=CC=C3)O
InChI
1S/C16H13NO2S/c1-19-13-9-7-12(8-10-13)16-17-15(18)14(20-16)11-5-3-2-4-6-11/h2-10,18H,1H3
InChIKey
YQAKORGQQCUKEJ-UHFFFAOYSA-N
PubChem Compound ID
Target and Pathway
Target(s) Arachidonate 5-lipoxygenase Target Info Inhibitor [531065]
BioCyc Pathway Aspirin-triggered lipoxin biosynthesis
Resolvin D biosynthesis
Leukotriene biosynthesis
Lipoxin biosynthesis
Aspirin triggered resolvin D biosynthesis
Aspirin triggered resolvin E biosynthesis
KEGG Pathway Arachidonic acid metabolism
Metabolic pathways
Serotonergic synapse
Ovarian steroidogenesis
Toxoplasmosis
NetPath Pathway IL4 Signaling Pathway
PathWhiz Pathway Arachidonic Acid Metabolism
WikiPathways Vitamin D Receptor Pathway
Arachidonic acid metabolism
Eicosanoid Synthesis
Selenium Micronutrient Network
References
Ref 531065J Med Chem. 1991 Jul;34(7):2158-65.4-hydroxythiazole inhibitors of 5-lipoxygenase.
Ref 531065J Med Chem. 1991 Jul;34(7):2158-65.4-hydroxythiazole inhibitors of 5-lipoxygenase.

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