Drug General Information
Drug ID	D05VSK
Former ID	DNC010061
Drug Name	ETHOXYCOUMARIN
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[530514]
Structure		Download 2D MOL 3D MOL
Formula	C11H10O3
Canonical SMILES	CCOC1=CC2=C(C=C1)C=CC(=O)O2
InChI	1S/C11H10O3/c1-2-13-9-5-3-8-4-6-11(12)14-10(8)7-9/h3-7H,2H2,1H3
InChIKey	LIFAQMGORKPVDH-UHFFFAOYSA-N
PubChem Compound ID	35703
Target and Pathway
Target(s)	Carbonic anhydrase	Target Info	Inhibitor	[530514]
	Carbonic anhydrase IX	Target Info	Inhibitor	[530514]
	Carbonic anhydrase XIV	Target Info	Inhibitor	[530514]
	Carbonic anhydrase XII	Target Info	Inhibitor	[530514]
KEGG Pathway	Nitrogen metabolismhsa00910:Nitrogen metabolismhsa00910:Nitrogen metabolism
NetPath Pathway	TGF_beta_Receptor Signaling Pathway
Pathway Interaction Database	HIF-1-alpha transcription factor network
Reactome	Regulation of gene expression by Hypoxia-inducible Factor
	Reversible hydration of carbon dioxideR-HSA-1475029:Reversible hydration of carbon dioxideR-HSA-1475029:Reversible hydration of carbon dioxide
WikiPathways	Vitamin D Receptor Pathway
	Reversible Hydration of Carbon Dioxide
	Regulation of Hypoxia-inducible Factor (HIF) by OxygenWP2770:Reversible Hydration of Carbon DioxideWP2770:Reversible Hydration of Carbon Dioxide
	miR-targeted genes in muscle cell - TarBase
	miR-targeted genes in leukocytes - TarBase
	miR-targeted genes in epithelium - TarBase
References
Ref 530514	J Med Chem. 2010 Jan 14;53(1):335-44.Deciphering the mechanism of carbonic anhydrase inhibition with coumarins and thiocoumarins.
Ref 530514	J Med Chem. 2010 Jan 14;53(1):335-44.Deciphering the mechanism of carbonic anhydrase inhibition with coumarins and thiocoumarins.

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