Drug Information

Drug General Information
Drug ID
D05WZK
Former ID
DIB019880
Drug Name
frescolat ML
Synonyms
(-)-menthyl lactate
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539594]
Structure
Download
2D MOL
Formula
C13H24O3
InChI
InChI=1S/C13H24O3/c1-8(2)11-6-5-9(3)7-12(11)16-13(15)10(4)14/h8-12,14H,5-7H2,1-4H3/t9-,10?,11+,12-/m1/s1
InChIKey
UJNOLBSYLSYIBM-SGUBAKSOSA-N
PubChem Compound ID
62151
PubChem Substance ID
8187905, 10544020, 14822858, 16387231, 25628216, 43119320, 50065637, 53800999, 76756494, 90454690, 104325093, 126622861, 126654340, 126685958, 135020134, 136903903, 142938834, 143500803, 152103505, 152164709, 152246177, 152250011, 163412428, 164239507, 184551574, 196111352, 226657982, 241101983, 246678956, 250144653
Target and Pathway
Target(s) TRPM8 protein Target Info Activator [526953]
KEGG Pathway Inflammatory mediator regulation of TRP channels
Reactome TRP channels
References
Ref 539594(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2466).
Ref 526953Characterization of the mouse cold-menthol receptor TRPM8 and vanilloid receptor type-1 VR1 using a fluorometric imaging plate reader (FLIPR) assay. Br J Pharmacol. 2004 Feb;141(4):737-45. Epub 2004Feb 2.

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