Drug General Information
Drug ID	D05XNR
Former ID	DNC003919
Drug Name	2,3-Dihydro-1H-indol-5-ol
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[551342]
Structure		Download 2D MOL 3D MOL
Formula	C8H9NO
Canonical SMILES	C1CNC2=C1C=C(C=C2)O
InChI	1S/C8H9NO/c10-7-1-2-8-6(5-7)3-4-9-8/h1-2,5,9-10H,3-4H2
InChIKey	MPCXQPXCYDDJSR-UHFFFAOYSA-N
PubChem Compound ID	10034684
Target and Pathway
Target(s)	D(2) dopamine receptor	Target Info	Inhibitor	[551342]
KEGG Pathway	Rap1 signaling pathway
	cAMP signaling pathway
	Neuroactive ligand-receptor interaction
	Gap junction
	Dopaminergic synapse
	Parkinson's disease
	Cocaine addiction
	Alcoholism
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
	Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
	Dopamine receptor mediated signaling pathway
	Nicotine pharmacodynamics pathway
Reactome	Dopamine receptors
	G alpha (i) signalling events
WikiPathways	Hypothetical Network for Drug Addiction
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	Genes and (Common) Pathways Underlying Drug Addiction
	GPCR ligand binding
	GPCR downstream signaling
	Nicotine Activity on Dopaminergic Neurons
References
Ref 551342	D4 dopamine receptor-selective compounds from the Chinese plant Phoebe chekiangensis, Bioorg. Med. Chem. Lett. 7(9):1207-1212 (1997).
Ref 551342	D4 dopamine receptor-selective compounds from the Chinese plant Phoebe chekiangensis, Bioorg. Med. Chem. Lett. 7(9):1207-1212 (1997).

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