Drug Information

Drug General Information
Drug ID
D06CZS
Former ID
DCL001126
Drug Name
V85546
Indication Inflammatory disease [ICD9: 140-229, 147, 173, 573.3, 710-719; ICD10:C11, C44, K75.9, M00-M25] Discontinued in Phase 1 [547917]
Therapeutic Class
Antiinflammatory Agents
Company
Vernalis
Target and Pathway
Target(s) MMP-12 Target Info Inhibitor [551758]
NetPath Pathway IL1 Signaling Pathway
IL5 Signaling Pathway
Pathway Interaction Database Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
Reactome Collagen degradation
Degradation of the extracellular matrix
WikiPathways TGF beta Signaling Pathway
Degradation of collagen
Matrix Metalloproteinases
References
Ref 547917Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800020392)
Ref 551758Clinical pipeline report, company report or official report of Vernalis.

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