Drug Information

Drug General Information
Drug ID
D06FEF
Former ID
DNC000644
Drug Name
Fedotozine
Drug Type
Small molecular drug
Indication Discovery agent Terminated [544798]
Structure
Download
2D MOL

3D MOL
Formula
C22H31NO4
Canonical SMILES
CCC(COCC1=CC(=C(C(=C1)OC)OC)OC)(C2=CC=CC=C2)N(C)C
InChI
1S/C22H31NO4/c1-7-22(23(2)3,18-11-9-8-10-12-18)16-27-15-17-13-19(24-4)21(26-6)20(14-17)25-5/h8-14H,7,15-16H2,1-6H3/t22-/m1/s1
InChIKey
MVKIWCDXKCUDEH-JOCHJYFZSA-N
CAS Number
CAS 123618-00-8
PubChem Compound ID
60764
PubChem Substance ID
43118113, 57314097, 77499921, 104321578, 117534117, 134222046, 135018704, 180370723, 227839088
Target and Pathway
Target(s) Kappa-type opioid receptor Target Info Agonist [535539]
KEGG Pathway Neuroactive ligand-receptor interaction
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Opioid prodynorphin pathway
Reactome Peptide ligand-binding receptors
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 544798Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001140)
Ref 535539Irritable bowel syndrome neuropharmacology. A review of approved and investigational compounds. J Clin Gastroenterol. 2002 Jul;35(1 Suppl):S58-67.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.