Drug General Information
Drug ID	D06LIA
Former ID	DNC008171
Drug Name	N,4-dimethyl-3,4-dihydroquinazolin-2-amine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[529158]
Structure		Download 2D MOL 3D MOL
Formula	C10H13N3
Canonical SMILES	CC1C2=CC=CC=C2NC(=N1)NC
InChI	1S/C10H13N3/c1-7-8-5-3-4-6-9(8)13-10(11-2)12-7/h3-7H,1-2H3,(H2,11,12,13)
InChIKey	RSJLYEIETDMSCV-UHFFFAOYSA-N
PubChem Compound ID	44455897
Target and Pathway
Target(s)	5-hydroxytryptamine 5A receptor	Target Info	Inhibitor	[529158]
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Serotonergic synapse
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Reactome	Serotonin receptors
	G alpha (i) signalling events
WikiPathways	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 529158	Bioorg Med Chem Lett. 2008 Jan 1;18(1):262-6. Epub 2007 Oct 30.Cyclic guanidines as dual 5-HT5A/5-HT7 receptor ligands: optimising brain penetration.
Ref 529158	Bioorg Med Chem Lett. 2008 Jan 1;18(1):262-6. Epub 2007 Oct 30.Cyclic guanidines as dual 5-HT5A/5-HT7 receptor ligands: optimising brain penetration.

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