Drug Information

Drug General Information
Drug ID
D06MBI
Former ID
DIB019089
Drug Name
TG003
Synonyms
Clk inhibitor; TG003; TG 003; TG-003
Drug Type
Small molecular drug
Indication Discovery agent Investigative [541226]
Structure
Download
2D MOL

3D MOL
Formula
C13H15NO2S
InChI
InChI=1S/C13H15NO2S/c1-4-14-11-8-10(16-3)5-6-12(11)17-13(14)7-9(2)15/h5-8H,4H2,1-3H3/b13-7-
InChIKey
BGVLELSCIHASRV-QPEQYQDCSA-N
PubChem Compound ID
1893668
PubChem Substance ID
845636, 3896227, 9162503, 10318949, 12577314, 16338860, 17405452, 24278611, 25687204, 26758446, 32753954, 50105027, 50105028, 50105029, 53778000, 57409229, 80848732, 85239700, 87535463, 88957742, 90341206, 99302678, 103567465, 104098218, 105093889, 110756923, 121361514, 124360161, 124750081, 124842363, 124887371, 134597849, 135653343, 162249259, 163564848, 163565291, 163688390, 172919681, 174009343, 178102565, 179235813, 201760346, 204377882, 210275221, 210280860, 223958316, 229036152, 252160432, 252473615
Target and Pathway
Target(s) CDC-like kinase 2 Target Info Inhibitor [529213]
Cdc2-like kinase 1 Target Info Inhibitor [529213]
NetPath Pathway TCR Signaling Pathway
EGFR1 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
WikiPathways mRNA Processing
References
Ref 541226(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5942).
Ref 529213Proc Natl Acad Sci U S A. 2007 Dec 18;104(51):20523-8. Epub 2007 Dec 11.A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.

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