Drug General Information
Drug ID	D06MUZ
Former ID	DIB000113
Drug Name	SDZ-87-469
Drug Type	Small molecular drug
Indication	Coronary artery disease [ICD9: 410-414, 429.2; ICD10:I20-I25]		Terminated	[551702]
Company	Novartis AG
Structure		Download 2D MOL 3D MOL
Formula	C19H22ClNS
Canonical SMILES	c12scc(c1cccc2CN(C/C=C/C#CC(C)(C)C)C)Cl
CAS Number	CAS 87906-31-8
PubChem Compound ID	6918070
Target and Pathway
Target(s)	Squalene monooxygenase	Target Info	Modulator	[535827]
KEGG Pathway	Steroid biosynthesis
	Sesquiterpenoid and triterpenoid biosynthesis
	Metabolic pathways
	Biosynthesis of secondary metabolites
	Biosynthesis of antibiotics
PathWhiz Pathway	Steroid Biosynthesis
Reactome	Cholesterol biosynthesis
	Activation of gene expression by SREBF (SREBP)
References
Ref 551702	Chemotherapy of fungal diseases. 1990. Page(525-550).
Ref 535827	Effects of squalene epoxidase inhibitors on Candida albicans. Antimicrob Agents Chemother. 1992 Aug;36(8):1779-81.

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