Drug General Information
Drug ID	D06PUS
Former ID	DNC008721
Drug Name	3-(2-Bromophenyl)-2-thioxo-(1H )-quinazolin-4-one
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[529219]
Structure		Download 2D MOL 3D MOL
Formula	C14H9BrN2OS
Canonical SMILES	C1=CC=C2C(=C1)C(=O)N(C(=S)N2)C3=CC=CC=C3Br
InChI	1S/C14H9BrN2OS/c15-10-6-2-4-8-12(10)17-13(18)9-5-1-3-7-11(9)16-14(17)19/h1-8H,(H,16,19)
InChIKey	FHKTYFZUNGXFGS-UHFFFAOYSA-N
PubChem Compound ID	11427575
Target and Pathway
Target(s)	CAMP-specific 3',5'-cyclic phosphodiesterase 4B	Target Info	Inhibitor	[529219]
KEGG Pathway	Purine metabolism
	cAMP signaling pathway
	Morphine addiction
NetPath Pathway	IL5 Signaling Pathway
	IL2 Signaling Pathway
Reactome	DARPP-32 events
	G alpha (s) signalling events
WikiPathways	G Protein Signaling Pathways
	Myometrial Relaxation and Contraction Pathways
	Nuclear Receptors Meta-Pathway
	Opioid Signalling
References
Ref 529219	Eur J Med Chem. 2008 Jul;43(7):1349-59. Epub 2007 Dec 21.CODES, a novel procedure for ligand-based virtual screening: PDE7 inhibitors as an application example.
Ref 529219	Eur J Med Chem. 2008 Jul;43(7):1349-59. Epub 2007 Dec 21.CODES, a novel procedure for ligand-based virtual screening: PDE7 inhibitors as an application example.

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