Drug General Information
Drug ID	D06QVB
Former ID	DNC004907
Drug Name	4-(Naphthalene-1-sulfonyl)-phenylamine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[527463]
Structure		Download 2D MOL 3D MOL
Formula	C16H13NO2S
Canonical SMILES	C1=CC=C2C(=C1)C=CC=C2S(=O)(=O)C3=CC=C(C=C3)N
InChI	1S/C16H13NO2S/c17-13-8-10-14(11-9-13)20(18,19)16-7-3-5-12-4-1-2-6-15(12)16/h1-11H,17H2
InChIKey	WJMHQZIDRDGGIY-UHFFFAOYSA-N
PubChem Compound ID	44390054
Target and Pathway
Target(s)	5-hydroxytryptamine 6 receptor	Target Info	Inhibitor	[527463]
KEGG Pathway	Calcium signaling pathway
	cAMP signaling pathway
	Neuroactive ligand-receptor interaction
	Serotonergic synapse
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PathWhiz Pathway	Excitatory Neural Signalling Through 5-HTR 6 and Serotonin
Reactome	Serotonin receptors
	G alpha (s) signalling events
WikiPathways	Serotonin Receptor 4/6/7 and NR3C Signaling
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 527463	Bioorg Med Chem Lett. 2005 Mar 15;15(6):1707-11.1-(1-Naphthyl)piperazine as a novel template for 5-HT6 serotonin receptor ligands.
Ref 527463	Bioorg Med Chem Lett. 2005 Mar 15;15(6):1707-11.1-(1-Naphthyl)piperazine as a novel template for 5-HT6 serotonin receptor ligands.

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