Drug General Information
Drug ID	D06WHL
Former ID	DIB004606
Drug Name	NS-257
Synonyms	PD-144216
Indication	Cerebrovascular ischaemia [ICD9: 434.91; ICD10:I61-I63]		Terminated	[545132]
Company	NeuroSearch A/S
Structure		Download 2D MOL 3D MOL
Canonical SMILES	S(=O)(=O)(c1c2c(c3c(/C(=N/O)/C(=O)N3)c1)CN(C2)C)N(C)C
CAS Number	CAS 147750-87-6
Target and Pathway
Target(s)	Glutamate receptor AMPA subtype	Target Info	Antagonist	[533631]
References
Ref 545132	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002246)
Ref 533631	Characterization of the binding of [3H]NS 257, a novel competitive AMPA receptor antagonist, to rat brain membranes and brain sections. J Neurochem. 1995 Sep;65(3):1264-73.

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