Drug Information

Drug General Information
Drug ID
D07ATG
Former ID
DNCL001785
Drug Name
GSK2190914
Indication Asthma [ICD10:J45] Discontinued in Phase 2 [548500]
Company
GlaxoSmithKline
Target and Pathway
Target(s) Arachidonate 5-lipoxygenaseactivating protein Target Info Inhibitor [530488]
NetPath Pathway IL4 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
Leptin Signaling Pathway
PANTHER Pathway Inflammation mediated by chemokine and cytokine signaling pathway
WikiPathways Nuclear Receptors Meta-Pathway
Arachidonic acid metabolism
Eicosanoid Synthesis
Selenium Micronutrient Network
References
Ref 548500Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800026047)
Ref 530488FLAP inhibitors for the treatment of inflammatory diseases. Curr Opin Investig Drugs. 2009 Nov;10(11):1163-72.

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