Drug Information

Drug General Information
Drug ID
D07AXM
Former ID
DIB018646
Drug Name
5-fluorotryptamine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [538930]
Structure
Download
2D MOL
Formula
C10H11FN2
InChI
InChI=1S/C10H11FN2/c11-8-1-2-10-9(5-8)7(3-4-12)6-13-10/h1-2,5-6,13H,3-4,12H2
InChIKey
ZKIORVIXEWIOGB-UHFFFAOYSA-N
PubChem Compound ID
164682
PubChem Substance ID
5564434, 7735714, 10255559, 11221143, 15147279, 41877473, 46238839, 47440683, 47811154, 57350523, 57565612, 57983926, 77830661, 85209828, 88542503, 92240011, 92722377, 99216130, 103100551, 103179297, 104860800, 113454595, 117509425, 117664556, 118055462, 123058997, 123110404, 124575378, 125325324, 125353490, 126580222, 126614834, 126618325, 126649600, 126662649, 127352012, 129915247, 131382028, 134348499, 135121714, 135649833, 135722527, 136376874, 136908893, 140114969, 143393605, 143493180, 152243162, 160812643, 162081812
Target and Pathway
Target(s) 5-hydroxytryptamine 1E receptor Target Info Agonist [526943]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
5HT1 type receptor mediated signaling pathway
Reactome Serotonin receptors
G alpha (i) signalling events
WikiPathways Serotonin HTR1 Group and FOS Pathway
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 538930(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 146).
Ref 526943Molecular cloning and pharmacological characterization of the guinea pig 5-HT1E receptor. Eur J Pharmacol. 2004 Jan 26;484(2-3):127-39.

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