Drug General Information
Drug ID	D07EJY
Former ID	DIB006043
Drug Name	AR-12286
Synonyms	AR-11236; AR-12080; AR-12132; CF-286-03; CF-286-04
Indication	Glaucoma [ICD9: 365; ICD10:H40-H42]		Phase 2	[524084]
Company	Aerie Pharmaceuticals Inc
Structure		Download 2D MOL 3D MOL
Canonical SMILES	c1nccc2c1ccc(c2)NC(=O)C(CC1CCCCC1)NC
Target and Pathway
Target(s)	Rho associated protein kinase	Target Info	Modulator	[531577]
References
Ref 524084	ClinicalTrials.gov (NCT01699464) A Study Assessing the Safety and Ocular Hypotensive Efficacy of AR-12286 in Patients With Elevated Intraocular Pressure for 3 Months. U.S. National Institutes of Health.
Ref 531577	Ocular hypotensive effect of the Rho kinase inhibitor AR-12286 in patients with glaucoma and ocular hypertension. Am J Ophthalmol. 2011 Nov;152(5):834-41.e1.

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