Drug Information

Drug General Information
Drug ID
D07GMY
Former ID
DNC000351
Drug Name
BRL 52974
Drug Type
Small molecular drug
Indication Discovery agent Investigative [534953]
Structure
Download
2D MOL

3D MOL
Formula
C19H22Cl2N4O
Canonical SMILES
C1CCN(C1)CC2C3=C(CCN2C(=O)CC4=CC(=C(C=C4)Cl)Cl)NC=N3
InChI
1S/C19H22Cl2N4O/c20-14-4-3-13(9-15(14)21)10-18(26)25-8-5-16-19(23-12-22-16)17(25)11-24-6-1-2-7-24/h3-4,9,12,17H,1-2,5-8,10-11H2,(H,22,23)
InChIKey
CJLJXCDVYJKDTR-UHFFFAOYSA-N
PubChem Compound ID
10000638
PubChem Substance ID
14980342, 22435529, 44092753, 79982417, 127634111, 135262878, 162400538, 162792915, 224929323, 233234126
Target and Pathway
Target(s) Kappa-type opioid receptor Target Info Agonist [534953]
KEGG Pathway Neuroactive ligand-receptor interaction
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Opioid prodynorphin pathway
Reactome Peptide ligand-binding receptors
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 534953The antitussive activity of delta-opioid receptor stimulation in guinea pigs. J Pharmacol Exp Ther. 2000 Feb;292(2):803-9.
Ref 534953The antitussive activity of delta-opioid receptor stimulation in guinea pigs. J Pharmacol Exp Ther. 2000 Feb;292(2):803-9.

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