Drug General Information
Drug ID
D07HBX
Former ID
DAP000731
Drug Name
Salicyclic acid
Synonyms
Domerine; Duofilm; Duoplant; Freezone; Ionil; Keralyt; Occlusal; Rutranex; SAX; Salicylate; Saligel; Salonil; Sebucare; Sebulex; Verrugon; Acido salicilico; Acido salicilico [Italian]; Acidum salicylicum; Advanced pain relief callus removers; Advanced pain relief corn removers; Akurza Cream; Akurza Lotion; Clear away wart remover; DHS Sal Shampoo; DuoPlant Gel; Duofil wart remover; Hydrisalic Gel; Ionil plus; Kyselina salicylova; Kyselina salicylova [Czech]; Mediplast pads; O Hydroxybenzoic Acid; Ortho Hydroxybenzoic Acid; Orthohydroxybenzoic acid; Retarder SAX; Retarder W; Salex Cream; Salex Lotion; Salicylic acid; Salicylic acid collodion; Salicylic acid soap; CMC_13852; K 537; ATA fraction 10, ammonium salt; Acid, Salicylic; Acido o-idrossibenzoico; Acido o-idrossibenzoico [Italian]; Ionil-Plus; Kyselina 2-hydroxybenzoova; Kyselina 2-hydroxybenzoova [Czech]; O-Carboxyphenol; O-hydroxybenzoic acid; Ortho-Hydroxybenzoic Acid; P&S Shampoo; Phenol derivative, 7; Propa pH Peel-Off Acne Mask; SALICYLIC ACID (SEE ALSO ALPHA HYDROXY ACIDS); SALICYLIC ACID, ACS; Salicylic acid & Sulfur Soap; Salicylic acid (TN); Salicylic acid [USAN:JAN]; Salicylic acid, tech; Stri-Dex; Acid, 2-Hydroxybenzoic; Acid, o-Hydroxybenzoic; Acid, ortho-Hydroxybenzoic; BENZOIC ACID,2-HYDROXY SALICYLIC ACID; Dr. Scholl's callus removers; Dr. Scholl's corn removers; Dr. Scholl's wart remover kit; Phenol-2-carboxylic acid; Psoriacid-S-stift; Salicylic acid (6CI,8CI); Salicylic acid (JP15/USP); Salicylic acid, tech.; Trans-Ver-Sal; Alpha/Beta Hydroxy Acids (Glycolic Acid, Salicylic Acid); Salicylic acid-ring-UL-14C; ALPHA/BETA HYDROXY ACIDS (SALICYLIC ACID) (SEE ALPHA/BETA HYDROXY ACIDS); Benzoic acid, 2-hydroxy-(9CI); E9A559BE-383B-4F83-BC02-3031D03D558A; 2 Hydroxybenzoic Acid; 2-Carboxyphenol; 2-Hydroxybenzenecarboxylic acid; 2-Hydroxybenzoic acid; 2-hydroxy(1-14c)benzoic acid
Drug Type
Small molecular drug
Indication Acne vulgaris; Dermatitis [ICD9: 706.1, 692.9; ICD10:L70.0, L20-L30] Approved [467646], [550757], [551871]
Therapeutic Class
Antiinflammatory Agents
Structure
Download
2D MOL

3D MOL

Formula
C7H6O3
InChI
InChI=1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)
InChIKey
YGSDEFSMJLZEOE-UHFFFAOYSA-N
CAS Number
CAS 69-72-7
PubChem Compound ID
PubChem Substance ID
ChEBI ID
ChEBI:16914
SuperDrug ATC ID
D01AE12; S01BC08
SuperDrug CAS ID
cas=000069727
Target and Pathway
Target(s) Prostaglandin G/H synthase 1 Target Info Inhibitor [536770]
BioCyc Pathway C20 prostanoid biosynthesis
KEGG Pathway Arachidonic acid metabolism
Metabolic pathways
Platelet activation
Serotonergic synapse
NetPath Pathway TGF_beta_Receptor Signaling Pathway
PANTHER Pathway Inflammation mediated by chemokine and cytokine signaling pathway
PathWhiz Pathway Arachidonic Acid Metabolism
WikiPathways Prostaglandin Synthesis and Regulation
Arachidonic acid metabolism
Phase 1 - Functionalization of compounds
Eicosanoid Synthesis
Selenium Micronutrient Network
References
Ref 467646(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4306).
Ref 550757Drug information of Salicyclic acid, 2008. eduDrugs.
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 536770The C50T polymorphism of the cyclooxygenase-1 gene and the risk of thrombotic events during low-dose therapy with acetyl salicylic acid. Thromb Haemost. 2008 Jul;100(1):70-5.

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