TTD | Drug: D07JDU

Drug General Information
Drug ID	D07JDU
Former ID	DNC010166
Drug Name	SB-706375
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[539372]
Structure		Download 2D MOL 3D MOL
Formula	C20H22BrF3N2O5S
InChI	InChI=1S/C20H22BrF3N2O5S/c1-26-7-6-13(11-26)31-16-8-12(4-5-14(16)20(22,23)24)25-32(27,28)19-10-18(30-3)17(29-2)9-15(19)21/h4-5,8-10,13,25H,6-7,11H2,1-3H3/t13-/m1/s1
InChIKey	BPOWQJYAMDEAFF-CYBMUJFWSA-N
PubChem Compound ID	21023902
PubChem Substance ID	34729316, 103596982, 104103997, 119693274, 134347371, 135651016, 139078072, 143249079, 163625521, 172918562, 231620020, 241377113, 244307064, 249691250, 252158258
Target and Pathway
Target(s)	Urotensin II receptor	Target Info	Inhibitor	[530610]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Peptide ligand-binding receptors
Reactome	G alpha (q) signalling events
WikiPathways	Gastrin-CREB signalling pathway via PKC and MAPK
	GPCR ligand binding
	GPCR downstream signaling
	GPCRs, Other
References
Ref 539372	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2165).
Ref 530610	J Med Chem. 2010 Apr 8;53(7):2695-708.Urotensin-II receptor modulators as potential drugs.

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Drug Information