Drug General Information
Drug ID	D07LIE
Former ID	DNC006788
Drug Name	2-(3-benzenesulfonyl)phenyl-1-aminoethane
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[528373]
Structure		Download 2D MOL 3D MOL
Formula	C14H15NO2S
Canonical SMILES	C1=CC=C(C=C1)S(=O)(=O)C2=CC=CC(=C2)CCN
InChI	1S/C14H15NO2S/c15-10-9-12-5-4-8-14(11-12)18(16,17)13-6-2-1-3-7-13/h1-8,11H,9-10,15H2
InChIKey	PXOKRWBUDGQCDL-UHFFFAOYSA-N
PubChem Compound ID	11849199
Target and Pathway
Target(s)	5-hydroxytryptamine 6 receptor	Target Info	Inhibitor	[528373]
KEGG Pathway	Calcium signaling pathway
	cAMP signaling pathway
	Neuroactive ligand-receptor interaction
	Serotonergic synapse
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PathWhiz Pathway	Excitatory Neural Signalling Through 5-HTR 6 and Serotonin
Reactome	Serotonin receptors
	G alpha (s) signalling events
WikiPathways	Serotonin Receptor 4/6/7 and NR3C Signaling
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 528373	J Med Chem. 2006 Aug 24;49(17):5217-25.Binding of sulfonyl-containing arylalkylamines at human 5-HT6 serotonin receptors.
Ref 528373	J Med Chem. 2006 Aug 24;49(17):5217-25.Binding of sulfonyl-containing arylalkylamines at human 5-HT6 serotonin receptors.

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