Drug Information

Drug General Information
Drug ID
D07TEB
Former ID
DIB018335
Drug Name
[3H]meta-chlorophenylbiguanide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539457]
Structure
Download
2D MOL
Formula
C8H10ClN5
InChI
InChI=1S/C8H10ClN5/c9-5-2-1-3-6(4-5)13-8(12)14-7(10)11/h1-4H,(H6,10,11,12,13,14)
InChIKey
DIHXJZHAIHGSAW-UHFFFAOYSA-N
PubChem Compound ID
1354
PubChem Substance ID
586256, 5286670, 7223051, 7941910, 7978566, 11110885, 11113502, 15220229, 24439695, 26751722, 47440465, 47662501, 48185177, 50064808, 50104412, 53837813, 57320880, 57756207, 59801931, 75031824, 81093350, 85787814, 87967146, 89578907, 90340725, 103176250, 103826501, 103950294, 104297494, 106772062, 107893064, 117460323, 117524446, 117832248, 118370216, 124749636, 124879493, 124879494, 124879495, 125668006, 127738970, 135071978, 135650380, 135651162, 136350445, 137129162, 137147747, 137230980, 139625845, 162220869
Target and Pathway
Target(s) 5-hydroxytryptamine receptor 3A Target Info Agonist [534584]
KEGG Pathway Serotonergic synapse
NetPath Pathway IL2 Signaling Pathway
PANTHER Pathway 5HT3 type receptor mediated signaling pathway
Reactome Ligand-gated ion channel transport
WikiPathways SIDS Susceptibility Pathways
Iron uptake and transport
References
Ref 539457(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2304).
Ref 534584Different efficacy of specific agonists at 5-HT3 receptor splice variants: the role of the extra six amino acid segment. Br J Pharmacol. 1998 Feb;123(4):661-6.

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