TTD | Drug: D07TKE

Drug General Information
Drug ID	D07TKE
Former ID	DNC007495
Drug Name	4-phenyl-1-(3-phenylpropyl)piperidin-4-ol
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[528785]
Structure		Download 2D MOL 3D MOL
Formula	C20H25NO
Canonical SMILES	C1CN(CCC1(C2=CC=CC=C2)O)CCCC3=CC=CC=C3
InChI	1S/C20H25NO/c22-20(19-11-5-2-6-12-19)13-16-21(17-14-20)15-7-10-18-8-3-1-4-9-18/h1-6,8-9,11-12,22H,7,10,13-17H2
InChIKey	ZZUJERGWKSXINO-UHFFFAOYSA-N
PubChem Compound ID	15723894
Target and Pathway
Target(s)	Nociceptin receptor	Target Info	Inhibitor	[528785]
KEGG Pathway	Neuroactive ligand-receptor interaction
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Reactome	Peptide ligand-binding receptors
Reactome	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 528785	Bioorg Med Chem Lett. 2007 Jun 1;17(11):3023-7. Epub 2007 Mar 23.Synthesis and structure-activity relationships of 4-hydroxy-4-phenylpiperidines as nociceptin receptor ligands: Part 1.
Ref 528785	Bioorg Med Chem Lett. 2007 Jun 1;17(11):3023-7. Epub 2007 Mar 23.Synthesis and structure-activity relationships of 4-hydroxy-4-phenylpiperidines as nociceptin receptor ligands: Part 1.

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Drug Information