Drug Information

Drug General Information
Drug ID
D07UXB
Former ID
DIB018511
Drug Name
1-OH-PGE1
Synonyms
19-hydroxy-PGE1; 19-hydroxyprostaglandin E1; 19-OH PGE1
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539244]
Structure
Download
2D MOL
Formula
C20H34O6
InChI
InChI=1S/C20H34O6/c1-14(21)7-6-8-15(22)11-12-17-16(18(23)13-19(17)24)9-4-2-3-5-10-20(25)26/h11-12,14-17,19,21-22,24H,2-10,13H2,1H3,(H,25,26)/b12-11+/t14?,15-,16+,17+,19+/m0/s1
InChIKey
QVVXWHIDRKRPMO-LXCOYWBSSA-N
PubChem Compound ID
6438402
PubChem Substance ID
11968061, 15124960, 43031405, 47734232, 57368048, 77920129, 114556040, 135076173, 135651385
Target and Pathway
Target(s) Prostaglandin E2 receptor, EP4 subtype Target Info Agonist [534478]
KEGG Pathway Neuroactive ligand-receptor interaction
Inflammatory mediator regulation of TRP channels
Renin secretion
Pathways in cancer
NetPath Pathway FSH Signaling Pathway
IL2 Signaling Pathway
IL4 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
Reactome Prostanoid ligand receptors
G alpha (s) signalling events
WikiPathways Prostaglandin Synthesis and Regulation
GPCRs, Class A Rhodopsin-like
Vitamin D Receptor Pathway
Small Ligand GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 539244(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1944).
Ref 534478Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells. Br J Pharmacol. 1997 Sep;122(2):217-24.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.