Drug General Information
Drug ID	D07VEW
Former ID	DNC000512
Drug Name	DADMe-ImmG
Indication	Discovery agent		Investigative	[535759]
Structure		Download 2D MOL 3D MOL
Formula	C12H16N4O3
Target and Pathway
Target(s)	Purine nucleoside phosphorylase	Target Info	Inhibitor	[535759]
BioCyc Pathway	Arsenate detoxification I (glutaredoxin)
	Purine nucleotides degradation
	Urate biosynthesis/inosine 5'-phosphate degradation
	Purine deoxyribonucleosides degradation
	Purine ribonucleosides degradation to ribose-1-phosphate
	Guanosine nucleotides degradation
	Adenosine nucleotides degradation
	Superpathway of purine nucleotide salvage
	Adenine and adenosine salvage III
	Guanine and guanosine salvage
KEGG Pathway	Purine metabolism
	Pyrimidine metabolism
	Nicotinate and nicotinamide metabolism
	Metabolic pathways
NetPath Pathway	TCR Signaling Pathway
	EGFR1 Signaling Pathway
PANTHER Pathway	Adenine and hypoxanthine salvage pathway
	Xanthine and guanine salvage pathway
PathWhiz Pathway	Purine Metabolism
	Nicotinate and Nicotinamide Metabolism
Reactome	Purine salvage
	Purine catabolism
WikiPathways	miR-targeted genes in squamous cell - TarBase
	miR-targeted genes in lymphocytes - TarBase
	miR-targeted genes in leukocytes - TarBase
	miR-targeted genes in epithelium - TarBase
	Metabolism of nucleotides
References
Ref 535759	Achieving the ultimate physiological goal in transition state analogue inhibitors for purine nucleoside phosphorylase. J Biol Chem. 2003 Aug 22;278(34):31465-8. Epub 2003 Jul 3.
Ref 535759	Achieving the ultimate physiological goal in transition state analogue inhibitors for purine nucleoside phosphorylase. J Biol Chem. 2003 Aug 22;278(34):31465-8. Epub 2003 Jul 3.

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