TTD | Drug: D07XLQ

Drug General Information
Drug ID	D07XLQ
Former ID	DNC009919
Drug Name	N-{4-[2-(4-Methoxyphenyl)ethyl]phenyl}phthalimide
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[530220]
Structure		Download 2D MOL 3D MOL
Formula	C23H19NO3
Canonical SMILES	COC1=CC=C(C=C1)CCC2=CC=C(C=C2)N3C(=O)C4=CC=CC=C4C3=O
InChI	1S/C23H19NO3/c1-27-19-14-10-17(11-15-19)7-6-16-8-12-18(13-9-16)24-22(25)20-4-2-3-5-21(20)23(24)26/h2-5,8-15H,6-7H2,1H3
InChIKey	CRWGIKAUSJNKIC-UHFFFAOYSA-N
PubChem Compound ID	44537911
Target and Pathway
Target(s)	Oxysterols receptor LXR-alpha	Target Info	Inhibitor	[530220]
KEGG Pathway	PPAR signaling pathway
	Non-alcoholic fatty liver disease (NAFLD)
	Hepatitis C
Pathway Interaction Database	RXR and RAR heterodimerization with other nuclear receptor
WikiPathways	Nuclear Receptors in Lipid Metabolism and Toxicity
	Nuclear Receptors Meta-Pathway
	PPAR Alpha Pathway
	Liver X Receptor Pathway
	Adipogenesis
	SREBF and miR33 in cholesterol and lipid homeostasis
	Nuclear Receptors
References
Ref 530220	Bioorg Med Chem. 2009 Jul 15;17(14):5001-14. Epub 2009 Jun 2.Separation of alpha-glucosidase-inhibitory and liver X receptor-antagonistic activities of phenethylphenyl phthalimide analogs and generation of LXRalpha-selective antagonists.
Ref 530220	Bioorg Med Chem. 2009 Jul 15;17(14):5001-14. Epub 2009 Jun 2.Separation of alpha-glucosidase-inhibitory and liver X receptor-antagonistic activities of phenethylphenyl phthalimide analogs and generation of LXRalpha-selective antagonists.

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Drug Information