Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D07XVN
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| Former ID |
DAP000649
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| Drug Name |
Dexrazoxane
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| Synonyms |
Cardioxane; Desrazoxane; Dexrazoxano; Dexrazoxanum; Dextrorazoxane; Dyzoxane; Eucardion; Savene; TopoTect; Totect; Zinecard; Dexrazoxane HCl; Dexrazoxane hydrochloride; ADR 529; ICRF 187; ICRF 187 hydrochloride; Cardioxane (TN); Dexrazoxane (TN); Dexrazoxano [INN-Spanish]; Dexrazoxanum [INN-Latin]; ICRF-187; Totect (TN); Zinecard (TN); Dexrazoxane (USAN/INN); Dexrazoxane [USAN:BAN:INN]; Soluble ICRF (L-isosomer); Razoxane, (S)-Isomer; Totect, ICRF-187, Zinecard, Cardioxane, Dexrazoxane Hydrochloride;(+)-(S)-4,4'-Propylenedi-2,6-piperazinedione; (+)-1,2-Bis(3,5-dioxo-1-piperazinyl)propane; (+)-1,2-Bis(3,5-dioxopiperazin-1-yl)propane; (S)-(+)-1,2-Bis(3,5-dioxopiperazin-1-yl)propane; 2,6-Piperazinedione, 4,4'-(1-methyl-1,2-ethanediyl)bis-, (+)-(9CI); 4,4'-(2S)-propane-1,2-diyldipiperazine-2,6-dione; 4-[(2S)-2-(3,5-dioxopiperazin-1-yl)propyl]piperazine-2,6-dione; 4-[(2S)-2-(3,5-dioxopiperazin-1-yl)propyl]piperazine-2,6-dione hydrochloride
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| Drug Type |
Small molecular drug
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| Therapeutic Class |
Anticancer Agents
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| Company |
Pfizer Pharmaceuticals
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| Structure |
|
Download2D MOL |
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| Formula |
C11H16N4O4
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| InChI |
InChI=1S/C11H16N4O4/c1-7(15-5-10(18)13-11(19)6-15)2-14-3-8(16)12-9(17)4-14/h7H,2-6H2,1H3,(H,12,16,17)(H,13,18,19)/t7-/m0/s1
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| InChIKey |
BMKDZUISNHGIBY-ZETCQYMHSA-N
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| CAS Number |
CAS 24584-09-6
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| PubChem Compound ID | |||||
| PubChem Substance ID |
442425, 831389, 8194593, 11405762, 14774896, 14872576, 17397819, 43127718, 46505982, 46506541, 50012896, 50139412, 57318172, 75683665, 93166226, 93619796, 103693192, 104350333, 117600767, 126670108, 127536650, 131307062, 134337939, 135029834, 136376430, 137002682, 137241718, 141868796, 144205809, 152035811, 160812421, 160871504, 160963727, 162174646, 163089322, 170464709, 172080045, 172092159, 172860861, 174007392, 174476563, 174560588, 175266611, 176484596, 176484943, 177748989, 178103902, 179117166, 184816244, 198945773
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| ChEBI ID |
ChEBI:50223
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| SuperDrug ATC ID |
V03AF02
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| SuperDrug CAS ID |
cas=024584096
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| Target and Pathway | |||||
| Target(s) | DNA topoisomerase II | Target Info | Modulator | [556264] | |
| References | |||||
| Ref 538309 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 076068. | ||||
| Ref 542354 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7330). | ||||
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