TTD | Drug: D08BYK

Drug General Information
Drug ID	D08BYK
Former ID	DNC000760
Drug Name	Hypericum
Drug Type	Small molecular drug
Indication	Discovery agent		Phase 4	[522154]
Structure		Download 2D MOL 3D MOL
Formula	C9H12N2O4S
Canonical SMILES	CC1(C(N2C(S1)C(C2=O)NC=O)C(=O)O)C
InChI	1S/C9H12N2O4S/c1-9(2)5(8(14)15)11-6(13)4(10-3-12)7(11)16-9/h3-5,7H,1-2H3,(H,10,12)(H,14,15)/t4-,5+,7-/m1/s1
InChIKey	MDQGTDMBVJCTBN-JCGDXUMPSA-N
CAS Number	CAS 26305-03-3
PubChem Compound ID	9548591
PubChem Substance ID	14717772, 44691936, 57372589, 74521374, 92741930, 128580652, 134340093, 134340101, 134340349, 141645920, 162635306, 175442287, 236389938, 252823637
Target and Pathway
Target(s)	Sodium-dependent noradrenaline transporter	Target Info	Inhibitor	[534900]
PANTHER Pathway	Adrenaline and noradrenaline biosynthesis
Reactome	Na+/Cl- dependent neurotransmitter transporters
WikiPathways	Monoamine Transport
	NRF2 pathway
	Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
References
Ref 522154	ClinicalTrials.gov (NCT00557427) Hypericum vs Fluoxetine for Mild to Moderate Adolescent Depression. U.S. National Institutes of Health.
Ref 534900	The experimental and clinical pharmacology of St John's Wort (Hypericum perforatum L.). Mol Psychiatry. 1999 Jul;4(4):333-8.

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Drug Information