TTD | Drug: D08CKM

Drug General Information
Drug ID	D08CKM
Former ID	DNC003586
Drug Name	SB-258741
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[526655]
Structure		Download 2D MOL 3D MOL
Formula	C19H30N2O2S
Canonical SMILES	CC1CCN(CC1)CCC2CCCN2S(=O)(=O)C3=CC=CC(=C3)C
InChI	1S/C19H30N2O2S/c1-16-8-12-20(13-9-16)14-10-18-6-4-11-21(18)24(22,23)19-7-3-5-17(2)15-19/h3,5,7,15-16,18H,4,6,8-14H2,1-2H3/t18-/m1/s1
InChIKey	YVWGGGGMRDLOGA-GOSISDBHSA-N
PubChem Compound ID	9863250
Target and Pathway
Target(s)	5-hydroxytryptamine 7 receptor	Target Info	Inhibitor	[526655]
KEGG Pathway	Ras signaling pathway
	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Serotonergic synapse
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PathWhiz Pathway	Excitatory Neural Signalling Through 5-HTR 7 and Serotonin
Reactome	Serotonin receptors
Reactome	G alpha (s) signalling events
WikiPathways	Serotonin Receptor 4/6/7 and NR3C Signaling
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
	GPCRs, Other
References
Ref 526655	J Med Chem. 2003 Jul 3;46(14):2795-812.Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7).
Ref 526655	J Med Chem. 2003 Jul 3;46(14):2795-812.Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7).

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Drug Information