Drug General Information
Drug ID	D08FSD
Former ID	DIB014788
Drug Name	SER-100
Synonyms	ORL1 receptor agonists, Zealand Pharma; ZP-120; ZP-120C
Indication	Heart failure [ICD9: 428; ICD10:I50]		Phase 2	[521792]
Company	Zealand Pharma A/S
Structure		Download 2D MOL
Target and Pathway
Target(s)	Nociceptin receptor	Target Info	Agonist	[551680]
KEGG Pathway	Neuroactive ligand-receptor interaction
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
	Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Reactome	Peptide ligand-binding receptors
	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 521792	ClinicalTrials.gov (NCT00283361) ZP120 Add-on to Furosemide in Treatment of Acute or Sub-Acute Decompensated Heart Failure. U.S. National Institutes of Health.
Ref 551680	Clinical pipeline report, company report or official report of Serodus ASA.

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