Drug Information

Drug General Information
Drug ID
D08HVR
Former ID
DIB006947
Drug Name
Levodopa
Synonyms
Levodopa (optimized formulation, Parkinson's disease); More effective levodopa (Parkinson's disease), Orion; Levodopa (optimized formulation, Parkinson's disease), Orion
Drug Type
Small molecular drug
Indication Parkinson's disease [ICD9: 332; ICD10:G20] Approved [540492]
Company
Orion Corp
Structure
Download
2D MOL

3D MOL
Formula
C9H11NO4
InChI
InChI=1S/C9H11NO4/c10-6(9(13)14)3-5-1-2-7(11)8(12)4-5/h1-2,4,6,11-12H,3,10H2,(H,13,14)/t6-/m0/s1
InChIKey
WTDRDQBEARUVNC-LURJTMIESA-N
PubChem Compound ID
6047
PubChem Substance ID
3648, 222573, 555833, 3136680, 7847127, 7886892, 7979689, 8001566, 8143351, 8150164, 8153771, 10321285, 11111115, 11112155, 11335627, 11360866, 11363348, 11365910, 11368472, 11374316, 11376634, 11461838, 11466045, 11467165, 11484127, 11485710, 11488312, 11492354, 11494268, 11532916, 11537951, 15120911, 15219946, 17405017, 24277914, 24863554, 26613179, 26679497, 26719283, 26746620, 26753566, 29225059, 46508120, 47216726, 47291084, 47440197, 47440198, 47736420, 47810699, 47959681
Target and Pathway
Target(s) D(2) dopamine receptor Target Info Modulator [540492]
KEGG Pathway Rap1 signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Gap junction
Dopaminergic synapse
Parkinson's disease
Cocaine addiction
Alcoholism
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Dopamine receptor mediated signaling pathway
Nicotine pharmacodynamics pathway
Reactome Dopamine receptors
G alpha (i) signalling events
WikiPathways Hypothetical Network for Drug Addiction
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
Genes and (Common) Pathways Underlying Drug Addiction
GPCR ligand binding
GPCR downstream signaling
Nicotine Activity on Dopaminergic Neurons
References
Ref 540492(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3639).
Ref 540492(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3639).

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