Drug Information

Drug General Information
Drug ID
D08JOS
Former ID
DNC000508
Drug Name
D 2343
Drug Type
Small molecular drug
Indication Discovery agent Investigative [537806]
Structure
Download
2D MOL

3D MOL
Formula
C20H28ClNO3
Canonical SMILES
CC(C)(CCC1=CC=CC=C1OC)NCC(C2=CC=C(C=C2)O)O.Cl
InChI
1S/C20H27NO3.ClH/c1-20(2,13-12-16-6-4-5-7-19(16)24-3)21-14-18(23)15-8-10-17(22)11-9-15;/h4-11,18,21-23H,12-14H2,1-3H3;1H
InChIKey
BFOKVGMFWNPMJB-UHFFFAOYSA-N
CAS Number
CAS 72734-63-5
PubChem Compound ID
6917755
PubChem Substance ID
12013008, 43529182, 51693394, 114786909, 236524789
Target and Pathway
Target(s) Beta-2 adrenergic receptor Target Info Agonist [537806]
KEGG Pathway Calcium signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Endocytosis
Adrenergic signaling in cardiomyocytes
Salivary secretion
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Beta2 adrenergic receptor signaling pathway
Pathway Interaction Database Arf6 trafficking events
Arf6 signaling events
Reactome Adrenoceptors
G alpha (s) signalling events
WikiPathways Monoamine GPCRs
Calcium Regulation in the Cardiac Cell
GPCRs, Class A Rhodopsin-like
Vitamin D Receptor Pathway
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 537806A new beta 2-adrenoceptor agonist--D 2343--with long duration. Inhalation comparison with terbutaline in asthmatics. Allergy. 1984 Aug;39(6):485-9.
Ref 537806A new beta 2-adrenoceptor agonist--D 2343--with long duration. Inhalation comparison with terbutaline in asthmatics. Allergy. 1984 Aug;39(6):485-9.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.