Drug Information

Drug General Information
Drug ID
D08MRN
Former ID
DAP000506
Drug Name
Hexylcaine
Synonyms
Hexilcaina; Hexylcainum; Osmocaine; Hexylcaine [INN]; Cyclaine (TN); Hexilcaina [INN-Spanish]; Hexylcainum [INN-Latin]; Osmocaine (TN); (2-Cyclohexylamino-1-methylethyl) benzoate; 1-(Cyclohexylamino)-2-propanol benzoate (ester); 1-(cyclohexylamino)propan-2-yl benzoate; 2-Propanol, 1-(cyclohexylamino)-, benzoate (ester)
Drug Type
Small molecular drug
Indication Local anaesthetic [ICD10:R20.0] Approved [551871]
Anesthesia [ICD9: 338; ICD10:R20.0] Withdrawn from market [538409], [542208]
Therapeutic Class
Anesthetics
Company
Merck & Co
Structure
Download
2D MOL

3D MOL
Formula
C16H23NO2
InChI
InChI=1S/C16H23NO2/c1-13(12-17-15-10-6-3-7-11-15)19-16(18)14-8-4-2-5-9-14/h2,4-5,8-9,13,15,17H,3,6-7,10-12H2,1H3
InChIKey
DKLKMKYDWHYZTD-UHFFFAOYSA-N
CAS Number
CAS 532-77-4
PubChem Compound ID
10770
PubChem Substance ID
7846984, 8157802, 10525635, 11466816, 11467936, 11486571, 15020876, 29229231, 46506241, 47574639, 47721859, 47721860, 48170675, 49699365, 50022930, 50124095, 50897451, 57326453, 85788076, 103358344, 104324215, 117551385, 126408826, 134337799, 134976849, 136307715, 137008815, 160963819, 178103771, 179225807, 223442386, 224668640, 226420737, 249983020
Target and Pathway
Target(s) Sodium channel protein type 5 subunit alpha Target Info Blocker [536316]
KEGG Pathway Adrenergic signaling in cardiomyocytes
PathWhiz Pathway Muscle/Heart Contraction
Reactome Interaction between L1 and Ankyrins
WikiPathways SIDS Susceptibility Pathways
Cardiac Progenitor Differentiation
References
Ref 538409FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 008472.
Ref 542208(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7196).
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 536316How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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