TTD | Drug: D08NQA

Drug General Information
Drug ID	D08NQA
Former ID	DIB020447
Drug Name	MRS5698
Synonyms	MRS-5698; MRS 5698
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[543124]
Structure		Download 2D MOL
Formula	C28H23ClF2N6O3
InChI	InChI=1S/C28H23ClF2N6O3/c1-32-27(40)28-11-17(28)22(23(38)24(28)39)37-13-34-21-25(33-12-15-3-2-4-16(29)9-15)35-20(36-26(21)37)8-6-14-5-7-18(30)19(31)10-14/h2-5,7,9-10,13,17,22-24,38-39H,11-12H2,1H3,(H,32,40)(H,33,35,36)/t17-,22-,23+,24+,28+/m1/s1
InChIKey	LYLLLJJYBWLGHW-CIZVZKTGSA-N
PubChem Compound ID	57523213
PubChem Substance ID	137280815, 160707233, 160868231, 235625036, 249896089, 252158843, 252166631
Target and Pathway
Target(s)	Adenosine A3 receptor	Target Info	Agonist	[531894]
Reactome	Adenosine P1 receptors
Reactome	G alpha (i) signalling events
WikiPathways	Nucleotide GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCRs, Other
References
Ref 543124	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8421).
Ref 531894	Structure-guided design of A(3) adenosine receptor-selective nucleosides: combination of 2-arylethynyl and bicyclo[3.1.0]hexane substitutions. J Med Chem. 2012 May 24;55(10):4847-60.

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Drug Information