Drug General Information
Drug ID
D08RBC
Former ID
DAP000741
Drug Name
Escitalopram
Synonyms
Esertia; Escitalopram [INN]; Cipralex (TN); Escitalopram (INN); Esertia (TN); Lexapro (TN); S(+)-Citalopram; (+)-(S)-1-(3-(Dimethylamino)propyl)-1-(p-fluorophenyl)-5-phthalancarbonitrile; (1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile; (1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-2-benzofuran-5-carbonitrile; (S)-Citalopram
Drug Type
Small molecular drug
Indication Major depression [ICD9: 296.2, 296.3; ICD10:F32, F33] Approved [551871]
Therapeutic Class
Antidepressants
Company
Forest Laboratories
Structure
Download
2D MOL

3D MOL

Formula
C20H21FN2O
InChI
InChI=1S/C20H21FN2O/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20/h4-9,12H,3,10-11,14H2,1-2H3/t20-/m0/s1
InChIKey
WSEQXVZVJXJVFP-FQEVSTJZSA-N
CAS Number
CAS 128196-01-0
PubChem Compound ID
PubChem Substance ID
ChEBI ID
ChEBI:36791
SuperDrug ATC ID
N06AB10
SuperDrug CAS ID
cas=128196010
Target and Pathway
Target(s) Sodium-dependent serotonin transporter Target Info Inhibitor [537557]
KEGG Pathway Serotonergic synapse
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway 5HT1 type receptor mediated signaling pathway
5HT2 type receptor mediated signaling pathway
5HT3 type receptor mediated signaling pathway
5HT4 type receptor mediated signaling pathway
WikiPathways Monoamine Transport
SIDS Susceptibility Pathways
NRF2 pathway
Synaptic Vesicle Pathway
Serotonin Transporter Activity
References
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 537557Antidepressants and sleep: a review. Perspect Psychiatr Care. 2009 Jul;45(3):191-7.

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