Drug General Information
Drug ID	D08TKB
Former ID	DNC010873
Drug Name	1-(2-phenoxybenzyl)-1H-imidazole
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[551345]
Structure		Download 2D MOL 3D MOL
Formula	C16H14N2O
Canonical SMILES	C1=CC=C(C=C1)OC2=CC=CC=C2CN3C=CN=C3
InChI	1S/C16H14N2O/c1-2-7-15(8-3-1)19-16-9-5-4-6-14(16)12-18-11-10-17-13-18/h1-11,13H,12H2
InChIKey	DFVDKHRBBOONAK-UHFFFAOYSA-N
PubChem Compound ID	46889432
Target and Pathway
Target(s)	Cytochrome P450 19	Target Info	Inhibitor	[551345]
BioCyc Pathway	Superpathway of steroid hormone biosynthesis
	Estradiol biosynthesis II
	Estradiol biosynthesis I
KEGG Pathway	Steroid hormone biosynthesis
	Metabolic pathways
	Ovarian steroidogenesis
NetPath Pathway	FSH Signaling Pathway
PANTHER Pathway	Androgen/estrogene/progesterone biosynthesis
PathWhiz Pathway	Androgen and Estrogen Metabolism
Reactome	Endogenous sterols
WikiPathways	Metapathway biotransformation
	Tryptophan metabolism
	Oxidation by Cytochrome P450
	Ovarian Infertility Genes
	Metabolism of steroid hormones and vitamin D
	FSH signaling pathway
	Integrated Breast Cancer Pathway
	Phase 1 - Functionalization of compounds
References
Ref 551345	Novel highly potent and selective nonsteroidal aromatase inhibitors: synthesis, biological evaluation and structure-activity relationships investigation. J Med Chem. 2010 Jul 22;53(14):5347-51. doi: 10.1021/jm100319h.
Ref 551345	Novel highly potent and selective nonsteroidal aromatase inhibitors: synthesis, biological evaluation and structure-activity relationships investigation. J Med Chem. 2010 Jul 22;53(14):5347-51. doi: 10.1021/jm100319h.

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