Drug Information

Drug General Information
Drug ID
D08VHG
Former ID
DIB002699
Drug Name
RPL-554
Synonyms
RPL-565; VMX-554; VMX-565; PDE 3/PDE 4 inhibitors, Kings College; PDE3/4 inhibitors (respiratory therapeutics), Rhinopharma; PDE3/4 inhibitors (nasal, respiratory disease), Verona Pharma; Trequinsin analogs (respiratory therapeutics), Kings College/Vernalis/Rhinopharma
Drug Type
Small molecular drug
Indication Allergic rhinitis [ICD9: 472.0, 477, 995.3; ICD10:J00, J30, J31.0, T78.4] Phase 2 [525173]
Company
King's College London
Structure
Download
2D MOL

3D MOL
Formula
C26H31N5O4
Canonical SMILES
n1(c(=O)n2c(c/c/1=N\c1c(cc(cc1C)C)C)c1c(cc(c(c1)OC)OC)C<br />C2)CCNC(=O)N
PubChem Compound ID
9934746
Target and Pathway
Target(s) Phosphodiesterase (PDE) 3 Target Info Modulator
References
Ref 525173ClinicalTrials.gov (NCT02427165) Comparison of RPL554 With Placebo and Salbutamol in Asthmatic Patients. U.S. National Institutes of Health.

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