TTD | Drug: D08WIJ

Drug General Information
Drug ID	D08WIJ
Former ID	DNC006240
Drug Name	8-methyl-2-morpholino-7-phenoxy-4H-chromen-4-one
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[527870]
Structure		Download 2D MOL 3D MOL
Formula	C20H19NO4
Canonical SMILES	CC1=C(C=CC2=C1OC(=CC2=O)N3CCOCC3)OC4=CC=CC=C4
InChI	1S/C20H19NO4/c1-14-18(24-15-5-3-2-4-6-15)8-7-16-17(22)13-19(25-20(14)16)21-9-11-23-12-10-21/h2-8,13H,9-12H2,1H3
InChIKey	OOXOMHKMWGSWSD-UHFFFAOYSA-N
PubChem Compound ID	23586753
Target and Pathway
Target(s)	CGMP-inhibited 3',5'-cyclic phosphodiesterase A	Target Info	Inhibitor	[527870]
KEGG Pathway	Purine metabolism
	cGMP-PKG signaling pathway
	cAMP signaling pathway
	Morphine addiction
Reactome	cGMP effects
Reactome	G alpha (s) signalling events
WikiPathways	miR-targeted genes in muscle cell - TarBase
WikiPathways	miR-targeted genes in lymphocytes - TarBase
References
Ref 527870	Bioorg Med Chem Lett. 2006 Feb 15;16(4):969-73. Epub 2005 Nov 15.Analysis of anti-PDE3 activity of 2-morpholinochromone derivatives reveals multiple mechanisms of anti-platelet activity.
Ref 527870	Bioorg Med Chem Lett. 2006 Feb 15;16(4):969-73. Epub 2005 Nov 15.Analysis of anti-PDE3 activity of 2-morpholinochromone derivatives reveals multiple mechanisms of anti-platelet activity.

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Drug Information