Drug Information

Drug General Information
Drug ID
D09AMZ
Former ID
DAP000597
Drug Name
Enprofylline
Synonyms
Enprofilina; Enprofyllinum; Nilyph; Oxeze; P 5679; D-4028; Enprofilina [INN-Spanish]; Enprofylline [USAN:INN]; Enprofyllinum [INN-Latin]; Enprofylline (USAN/INN); 3,7-Dihydro-3-propyl-1H-purine-2,6-dione; 3-Propyl-3,7-dihydro-purine-2,6-dione; 3-Propylxanthine; 3-n-Propylxanthine; 3-propyl-3,7-dihydro-1H-purine-2,6-dione; 3-propyl-7H-purine-2,6-dione
Drug Type
Small molecular drug
Indication Asthma [ICD10:J45] Approved [537725]
Therapeutic Class
Antiinflammatory Agents
Structure
Download
2D MOL

3D MOL
Formula
C8H10N4O2
Canonical SMILES
CCCN1C2=C(C(=O)NC1=O)NC=N2
InChI
1S/C8H10N4O2/c1-2-3-12-6-5(9-4-10-6)7(13)11-8(12)14/h4H,2-3H2,1H3,(H,9,10)(H,11,13,14)
InChIKey
SIQPXVQCUCHWDI-UHFFFAOYSA-N
CAS Number
CAS 41078-02-8
PubChem Compound ID
1676
PubChem Substance ID
855784, 4285594, 8151233, 11111643, 12012874, 14772979, 15219898, 17398000, 17405468, 24277687, 26751510, 29220879, 46505790, 47365405, 47736695, 47810964, 48035338, 48110660, 50028023, 50100320, 50104067, 50104068, 53778016, 57320977, 72794359, 78817644, 85088984, 85209069, 85231189, 85331227, 90341781, 92304175, 103131576, 103188003, 103915958, 104171214, 104298395, 117600223, 121361566, 124750090, 124800765, 124881140, 124881141, 124881142, 124881143, 129241696, 132554404, 134222975, 134337888, 134338586
Target and Pathway
Target(s) CAMP-specific 3',5'-cyclic phosphodiesterase 4A Target Info Inhibitor [537725]
KEGG Pathway Purine metabolism
cAMP signaling pathway
Morphine addiction
Reactome DARPP-32 events
G alpha (s) signalling events
WikiPathways G Protein Signaling Pathways
References
Ref 537725Effects of enprofylline, a new xanthine derivate, on human pregnant myometrium. Am J Obstet Gynecol. 1987 Apr;156(4):958-62.
Ref 537725Effects of enprofylline, a new xanthine derivate, on human pregnant myometrium. Am J Obstet Gynecol. 1987 Apr;156(4):958-62.

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