Drug General Information
Drug ID	D09AOO
Former ID	DCL001141
Drug Name	ANAVEX 2-73
Indication	Breast cancer [ICD9: 174, 175; ICD10:C50]		Phase 2	[531153], [532266]
	Alzheimer disease [ICD9: 331; ICD10:G30]		Phase 1	[549727]
Company	Anavex
Structure		Download 2D MOL
Target and Pathway
Target(s)	Sigma(1)-type opioid receptor	Target Info	Agonist	[549727]
WikiPathways	miR-targeted genes in squamous cell - TarBase
	miR-targeted genes in lymphocytes - TarBase
References
Ref 531153	Anti-amnesic and neuroprotective potentials of the mixed muscarinic receptor/sigma 1 (?1) ligand ANAVEX2-73, a novel aminotetrahydrofuran derivative. J Psychopharmacol. 2011 Aug;25(8):1101-17.
Ref 532266	Blockade of Tau hyperphosphorylation and Abeta?????? generation by the aminotetrahydrofuran derivative ANAVEX2-73, a mixed muscarinic and ???receptor agonist, in a nontransgenic mouse model of Alzheimer's disease. Neuropsychopharmacology. 2013 Aug;38(9):1706-23.
Ref 549727	2011 Pipeline of Anavex.
Ref 549727	2011 Pipeline of Anavex.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.