Drug Information

Drug General Information
Drug ID
D09BLB
Former ID
DIB020340
Drug Name
methylcarbamyl PAF
Synonyms
methyl-carbamyl platelet-activating factor; mc-PAF
Drug Type
Small molecular drug
Indication Discovery agent Investigative [540369]
Structure
Download
2D MOL
Formula
C26H55N2O7P
InChI
InChI=1S/C26H55N2O7P/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21-32-23-25(35-26(29)27-2)24-34-36(30,31)33-22-20-28(3,4)5/h25H,6-24H2,1-5H3,(H-,27,29,30,31)/t25-/m1/s1
InChIKey
FNFHZBKBDFRYHS-RUZDIDTESA-N
PubChem Compound ID
124663
PubChem Substance ID
10241144, 24895650, 26754998, 26754999, 29304643, 50110864, 57341013, 78679115, 92309698, 99300612, 99302130, 104046572, 104421324, 135082142, 135651517, 137324603, 162228688, 163133710, 163831827, 164758086, 184021200, 184568115, 231325247, 241175900, 242392779, 250136936, 252370953, 252455422, 252457458, 252464695
Target and Pathway
Target(s) Platelet-activating factor receptor Target Info Agonist [543773]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Staphylococcus aureus infection
NetPath Pathway IL5 Signaling Pathway
Leptin Signaling Pathway
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (q) signalling events
Interferon gamma signaling
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Small Ligand GPCRs
Interferon gamma signaling
GPCR ligand binding
GPCR downstream signaling
References
Ref 540369(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3427).
Ref 543773(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 334).

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