Drug Information

Drug General Information
Drug ID
D09BYW
Former ID
DNC011584
Drug Name
N-[4-(4-Phenyl-piperazin-1-yl)-butyl]-benzamide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [533428]
Structure
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2D MOL

3D MOL
Formula
C21H27N3O
Canonical SMILES
C1CN(CCN1CCCCNC(=O)C2=CC=CC=C2)C3=CC=CC=C3
InChI
1S/C21H27N3O/c25-21(19-9-3-1-4-10-19)22-13-7-8-14-23-15-17-24(18-16-23)20-11-5-2-6-12-20/h1-6,9-12H,7-8,13-18H2,(H,22,25)
InChIKey
SPKHLKULRLEZKZ-UHFFFAOYSA-N
PubChem Compound ID
14162480
Target and Pathway
Target(s) 5-hydroxytryptamine 1A receptor Target Info Inhibitor [533428]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
5HT1 type receptor mediated signaling pathway
Reactome Serotonin receptors
G alpha (i) signalling events
WikiPathways Serotonin HTR1 Group and FOS Pathway
SIDS Susceptibility Pathways
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 533428J Med Chem. 1988 Oct;31(10):1968-71.Arylpiperazine derivatives as high-affinity 5-HT1A serotonin ligands.
Ref 533428J Med Chem. 1988 Oct;31(10):1968-71.Arylpiperazine derivatives as high-affinity 5-HT1A serotonin ligands.

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