Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D09DLP
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| Former ID |
DIB002636
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| Drug Name |
Tramiprosate
|
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| Synonyms |
Alzhemed; Cerebril; Homotaurine; Vivimind; LU-02659; NC-531; NC-758; Tramiprosate (stroke), Neurochem; Tramiprosate (Alzheimer's disease), Neurochem; 3APS
|
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| Drug Type |
Small molecular drug
|
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| Indication | Alzheimer disease [ICD9: 331; ICD10:G30] | Phase 3 | [521823] | ||
| Company |
Neurochem
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C3H9NO3S
|
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| Canonical SMILES |
S(=O)(=O)(O)CCCN
|
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| CAS Number |
CAS 3687-18-1
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Amyloid beta A4 protein | Target Info | Antagonist | [528183] | |
| KEGG Pathway | Notch signaling pathway | ||||
| Alzheimer's disease | |||||
| Reactome | Nuclear signaling by ERBB4 | ||||
| Degradation of the extracellular matrix | |||||
| Regulated proteolysis of p75NTR | |||||
| NRIF signals cell death from the nucleus | |||||
| Activated NOTCH1 Transmits Signal to the Nucleus | |||||
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | |||||
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | |||||
| EPH-ephrin mediated repulsion of cells | |||||
| References | |||||
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