Drug Information

Drug General Information
Drug ID
D09DRG
Former ID
DCL000893
Drug Name
NE-100
Synonyms
NE 100; N,N-diethyl-2-(4-methoxy-3-phenethyloxyphenyl)ethanamine hydrochloride; N,N-Dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride; Benzeneethanamine, 4-methoxy-3-(2-phenylethoxy)-N,N-dipropyl-, hydrochloride
Drug Type
Small molecular drug
Indication Schizophrenia [ICD9: 295; ICD10:F20] Terminated [536463], [541784]
Company
Taisho
Structure
Download
2D MOL

3D MOL
Formula
C23H33NO2
InChI
InChI=1S/C23H33NO2/c1-4-15-24(16-5-2)17-13-21-11-12-22(25-3)23(19-21)26-18-14-20-9-7-6-8-10-20/h6-12,19H,4-5,13-18H2,1-3H3
InChIKey
YBLIQJGXRLZBCZ-UHFFFAOYSA-N
CAS Number
CAS 69655-05-6
PubChem Compound ID
9841596
PubChem Substance ID
14803172, 24139683, 44939673, 50070643, 75131878, 103458141, 103857054, 104057040, 129771570, 178103291, 229264069
SuperDrug ATC ID
J05AF02
SuperDrug CAS ID
cas=069655056
Target and Pathway
Target(s) Sigma(1)-type opioid receptor Target Info Antagonist [536463]
WikiPathways miR-targeted genes in squamous cell - TarBase
miR-targeted genes in lymphocytes - TarBase
References
Ref 536463The pipeline and future of drug development in schizophrenia. Mol Psychiatry. 2007 Oct;12(10):904-22. Epub 2007 Jul 31.
Ref 541784(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6679).
Ref 536463The pipeline and future of drug development in schizophrenia. Mol Psychiatry. 2007 Oct;12(10):904-22. Epub 2007 Jul 31.

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