Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D09DUE
|
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| Former ID |
DNC007678
|
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| Drug Name |
MCL-447
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [528787] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C22H31N3O
|
||||
| Canonical SMILES |
C1CCC23CCN(C(C2C1)CC4=C3C=C(C=C4)NC(=O)N)CC5CCC5
|
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| InChI |
1S/C22H31N3O/c23-21(26)24-17-8-7-16-12-20-18-6-1-2-9-22(18,19(16)13-17)10-11-25(20)14-15-4-3-5-15/h7-8,13,15,18,20H,1-6,9-12,14H2,(H3,23,24,26)/t18-,20+,22+/m0/s1
|
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| InChIKey |
UYFRBZFZZCVVGT-CZTZKLFOSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Kappa-type opioid receptor | Target Info | Inhibitor | [528787] | |
| Delta-type opioid receptor | Target Info | Inhibitor | [528787] | ||
| Mu-type opioid receptor | Target Info | Inhibitor | [528787] | ||
| NetPath Pathway | TCR Signaling Pathway | ||||
| PANTHER Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | |||||
| Opioid prodynorphin pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||||
| Enkephalin release | |||||
| Opioid proenkephalin pathway | |||||
| Opioid proopiomelanocortin pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||||
| Pathway Interaction Database | IL4-mediated signaling events | ||||
| References | |||||
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